Sickle cell disease: Only one road, but different pathways for inflammation
نویسندگان
چکیده
منابع مشابه
Neonatal Screening for Sickle Cell Disease in Southwest Iran
the risk of sickle cell complications that is a common hemoglobin disorder in Southwest Iran. This study aimed at determining the incidence of Sickle Cell Disease (SCD) and other Hemoglobinopathies in newborn being at risk based on ethnic origin. Materials and Methods: In this descriptive epidemiologic study, between September 2013 and September 2015, 8363 newborn blood samples were test...
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In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...
متن کاملNewborn screening for sickle cell disease: necessary but not sufficient.
ickle cell disease is a global health problem that ffects > 300,000 newborns per year, predominantly in Subaharan Africa,1 where mortality is estimated to be > 50% y age 5 years for those with homozygous hemoglobin S HbSS).1 In Brazil, there are estimated to be > 30,000 indiiduals with sickle cell disease and 2,500 newborns per ear, making this the most common genetic disorder in the ountry.2 A...
متن کاملPulmonary hypertension in patients with sickle cell disease: not so frequent but so different.
U ntil recently, the prevalence and characteristics of pulmonary hypertension (PH) in adults with sickle cell disease remained uncertain. In previous studies, the prevalence of PH, as defined by a tricuspid valve regurgitant jet velocity (TRJV) of o2.5 m?s, has been reported as high as 30% [1, 2]. However, in these studies, the diagnosis of PH was not systematically confirmed on right heart cat...
متن کاملSickle-cell anaemia, sickle-cell thalassaemia, sickle-cell haemoglobin C disease, and asymptomatic haemoglobin C thalassaemia in one Ghanaian family.
A Ghanaian family is described in which a sickle-cell haemoglobin C man married to a sickle-cell thalassaemia woman produced 12 children (eight alive). Four children have sickle-cell anaemia, two sickle-cell haemoglobin C disease, one has sickle-cell thalassaemia, and one is asymptomatic haemoglobin C thalassaemia.It is emphasized that the contribution that adult sickle-cell disease patients ma...
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ژورنال
عنوان ژورنال: Advances in Bioscience and Biotechnology
سال: 2012
ISSN: 2156-8456,2156-8502
DOI: 10.4236/abb.2012.324071